Lactated Ringers Infusion
Sodium Chloride. 600 mg;Sodium Lactate 310 mg;Potassium Chloride 30 mg;Calcium Chloride 20 mg
Lactated Ringers Injection – Clinical Pharmacology
Lactated Ringer’s Injection has value as a source of water and electrolytes. It is capable of inducing diuresis depending on the clinical condition of the patient.
Lactated Ringer’s Injection produces a metabolic alkalinizing effect. Lactate ions are metabolized ultimately to carbon dioxide and water, which requires the consumption of hydrogen cations.
Indications and Usage for Lactated Ringers Injection
Lactated Ringer’s Injection is indicated as a source of water and electrolytes or as an alkalinizing agent.
As for other calcium-containing infusion solutions, concomitant administration of ceftriaxone and Lactated Ringer’s Injection is contraindicated in newborns (≤ 28 days of age), even if separate infusion lines are used (risk of fatal ceftriaxone-calcium salt precipitation in the neonate’s bloodstream).
In patients older than 28 days (including adults), ceftriaxone must not be administered simultaneously with intravenous calcium-containing solutions, including Lactated Ringer’s Injection, through the same infusion line (e.g., via Y-connector). If the same infusion line is used for sequential administration, the line must be thoroughly flushed between infusions with a compatible fluid.
Lactated Ringer’s Injection is contraindicated in patients with a known hypersensitivity to sodium lactate.